Contraindicated Use of Cisapride

Coprescribing and codispensing of cisapride and contraindicated drugs.

CONTEXT Cisapride, an oral prokinetic drug indicated for the symptomatic treatment of nocturnal heartburn due to gastroesophageal reflux disease, was approved by the US Food and Drug Administration in July 1993. After reports of serious cardiac arrhythmias and deaths during administration of cisapride, most involving concomitant exposure to another drug, a series of label changes and warnings w...

Increase in mortality rate following coprescription of cisapride and contraindicated drugs.

BACKGROUND No epidemiologic study, as of this writing, has been published on the use of cisapride with contraindicated drugs and its relation to mortality rates in a population-based setting. OBJECTIVE To estimate the prevalence of concomitant use of cisapride with contraindicated drugs and evaluate the association between this and the risk of mortality. METHODS Claims data were obtained fr...

Contraindicated medication use in dialysis patients undergoing percutaneous coronary intervention.

CONTEXT The US Food and Drug Administration guides clinicians through drug labeling of medications that are contraindicated or not recommended for use in specific patient groups. Little is known about the use of such medications and their effects on outcomes in clinical practice. OBJECTIVE To investigate the use of the contraindicated/not-recommended agents enoxaparin and eptifibatide among d...

Metformin's contraindications should be contraindicated.

the use of appropriate madm model for ranking the vendors of mci equipments using fuzzy approach

abstract nowadays, the science of decision making has been paid to more attention due to the complexity of the problems of suppliers selection. as known, one of the efficient tools in economic and human resources development is the extension of communication networks in developing countries. so, the proper selection of suppliers of tc equipments is of concern very much. in this study, a ...